The human endocannabinoid system is primarily made up of endocannabinoids, and receptors. Endocannabinoids are molecules produced by the human body, they bind to CB1 and CB2 receptors which are found all throughout the body. When endocannabinoids bind to receptors there are many potential effects to the body, depending on variables such as where in the body the receptors lie, and which type of receptors are binding with which type of endocannabinoids.
As the endocannabinoid system is not fully understood, many studies are currently under way to explore and map the system, and it’s various effects on the human body. Scientists have discovered receptors all throughout the body, including in the skin, liver, kidneys, blood vessels and gastrointestinal tract, among others. This system is believed to have an effect in digestive processes, mood, pain, appetite, stress, sleep, metabolism, and immune and reproductive function.
Endocannabinoids and Exercise
Scientific studies have demonstrated links between endocannabinoids and the experience of a ‘runner’s high’. People experience runner’s high after having participated in a long period of aerobic exercise. Runner’s high is characterized by feelings of lowered anxiety and increased tolerance for pain.
Endocannabinoids and Digestion
When food is being digested, endocannabinoids play a role in how quickly food moves through the digestive system, as well as taking part in the digestive process and protecting the body from stomach acids.
As the endocannabinoid system is studied further, the various ways in which it is active throughout the human body are coming to light.
Sources
MacKinnon, M. (N.D.), Why does pot make you so hungry? How cannabis affects our bodies and brains
Lavelle, J. (2015) New Brain Effects behind “Runner’s High”
Human Endocannabinoid System

